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11
May 2021
Pioneering CAR-T cell therapy locates and destroys deadly cancer cells in new trials
A new cancer treatment in which a patient’s own cells are engineered to seek and wipe out their disease, and then linger in the body to stop the cancer returning, is helping to save patients’ lives.
Trials have shown that patients, after undertaking the therapy, who had exhausted all other options and been told they had just months to live, have gone into remission. Others have been cured completely by the one-off dose.
In the trials, all signs of cancer disappeared in over 80 per cent of patients with acute lymphoblastic leukaemia, the most common cancer in children, after receiving CAR-T cells.
First given two years ago to children with the rare blood cancer, the therapy is now being used to treat four forms of the disease, and more could follow.
It is also being trialled on other blood cancers, such as non-Hodgkin lymphoma, myeloma and chronic lymphocytic leukaemia, and could soon be available for these patients.
Preliminary research has suggested it can also tackle solid tumours. A new study on mice reported by the journal Science Translational Medicine, has found that a new generation of CAR-T cells with further advanced genetic engineering could help treat ovarian cancer, mesothelioma and the potentially deadly brain cancer glioblastoma without side-effects.
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Posted by Karen Motley, Clinical Negligence Department, Chadwick Lawrence LLP (tonymay@chadlaw.co.uk ), medical negligence lawyers and clinical negligence solicitors in Huddersfield, Leeds, Wakefield and Halifax, West Yorkshire.
Freephone : 0800 304 7382
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