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17
Aug 2021
Fundraising launched for University of Leeds-led Sativex brain tumour trial
A bid has been launched to fund a medical trial of a cannabis-based mouth spray in treatment of the most aggressive form of brain tumour.
Researchers are looking into the use of cannabinoid-containing Sativex alongside chemotherapy treatment against recurrent glioblastoma.
Around 2,200 patients are diagnosed with this type of brain tumour each year in England, with the average survival rate of less than ten months.
The Brain Tumour Charity has launched an appeal to raise £450,000 to fund the scheme which is expected to last three years.
Sativex, which contains a mix of cannabidiol (CBD) and THC was approved for use on the NHS in 2019 to treat muscle spasms linked to multiple sclerosis.
Researchers want to measure whether adding the treatment to chemotherapy extends the overall length of patients’ lives, delays progression of the disease or improves quality of life.
If successful, the trial could represent one of the first additions to NHS glioblastoma treatment in over a decade.
The trial, led by University of Leeds and coordinated by a specialist research unit at the University of Birmingham, is due to start the recruitment of more than 230 patients across the UK in 2022.
Professor Susan Short, professor of clinical oncology and neuro oncology at the University of Leeds, said “Even with surgery, radiotherapy and chemotherapy, nearly all of these brain tumours re-grow within a year, and unfortunately there are very few options for patients once this occurs.
“Having recently shown that a specific cannabinoid combination given by oral spray could be safely added to temozolomide chemotherapy, we’re really excited to build on these findings to assess whether this drug could help glioblastoma patients live longer.”
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Posted by Karen Motley, Clinical Negligence Department, Chadwick Lawrence LLP (tonymay@chadlaw.co.uk ), medical negligence lawyers and clinical negligence solicitors in Huddersfield, Leeds, Wakefield and Halifax, West Yorkshire.
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